About HumanGeneAI

Advancing genetic research through AI-powered intelligence

Our Mission

HumanGeneAI is dedicated to democratizing access to comprehensive genetic information through cutting-edge artificial intelligence. Our platform bridges the gap between complex genomic data and actionable insights, empowering researchers, clinicians, and scientists worldwide with personalized genetic analysis.

We believe that genetic information should be accessible, understandable, and actionable. By integrating multiple authoritative databases with AI-powered analysis that considers individual biological factors, ethnicity, and geographic background, we're creating a unified platform that accelerates genetic research and provides personalized genetic insights.

Platform Overview

6+
Integrated Databases
50K+
Human Genes
99.9%
Uptime
Real-time
Data Updates

Key Features

πŸ” Multi-Database Search

Search across 7 major genetic databases simultaneously, providing comprehensive gene information in one unified interface with direct linkouts to source databases.

πŸ€– AI-Powered Analysis

Advanced AI algorithms provide intelligent insights, personalized gene recommendations based on biological factors, and research trends analysis.

πŸ’¬ AI Chat Assistant

Natural language chat interface powered by OpenAI for asking complex genetic questions and receiving AI-assisted interpretations of genetic data in plain language.

🧬 Personalized Recommendations

AI-driven gene suggestions based on age, gender, ethnicity, geographic location, and health profile for targeted genetic insights.

οΏ½ Clinical Trials & Drug Data

Real-time access to ClinicalTrials.gov and PharmGKB for drug interactions, clinical studies, and pharmacogenomic guidelines.

πŸ•ΈοΈ Gene Association Networks

Interactive gene association analysis using Hetionet biomedical knowledge graphs to explore gene-disease-compound relationships.

πŸ“Š Advanced Gene Analytics

Machine learning-powered analytics with 193,640+ gene records, optimized database performance, and sub-100ms query response times.

πŸ”— Smart Alias Resolution

Automatically resolves gene aliases and displays comprehensive gene symbol mappings across all integrated databases.

πŸ“ˆ Real-time Trending

AI-powered analysis of trending genes from PubMed, clinical trials, biotech news, and research conferences.

🌍 Population Genetics

Ethnicity and geographic-specific genetic variants and disease risk assessments for diverse populations worldwide.

⚑ High-Performance Database

Optimized HumanGeneAIDB with performance indexes, advanced query optimization, and enterprise-grade reliability.

πŸ“± Responsive Design

Optimized for desktop, tablet, and mobile devices with an intuitive, modern interface and seamless cross-platform experience.

Integrated Databases & APIs

HumanGeneAI retrieves and integrates information from the world's most authoritative genetic and clinical databases:

🧬 Core Genetic Databases (7)

MyGene.info

Primary gene annotation service with high-performance APIs and comprehensive gene information

NCBI Gene

National Center for Biotechnology Information - official gene database

HGNC

HUGO Gene Nomenclature Committee - official gene symbols and nomenclature

Ensembl

European genome annotation project from EMBL-EBI with detailed genomic data

UCSC Genome Browser

University of California Santa Cruz genome browser and visualization tools

UniProt

Universal Protein Resource for protein sequences, functions, and annotations

ProteinAtlas

Human Protein Atlas - tissue-specific protein expression and localization data

πŸ’Š Clinical & Pharmacogenomics APIs (2)

ClinicalTrials.gov API

Official U.S. database of clinical studies - real-time clinical trial information and drug studies

PharmGKB

Pharmacogenomics Knowledgebase - drug-gene interactions and clinical guidelines

πŸ“Š Internal Database

HumanGeneAIDB

Our optimized gene database with 193,640+ gene records, 34 performance indexes, and sub-100ms query response times

πŸ”— External Link-outs & References (4)

OMIM

Online Mendelian Inheritance in Man - comprehensive database of human genes and genetic phenotypes

VEGA Archive

Vertebrate Genome Annotation project - archived reference gene annotation from Ensembl

Hetionet

Biomedical knowledge graph connecting genes, compounds, diseases, and biological processes

GenomeNames.org

Direct links to HGNC gene nomenclature data and gene symbol reports

Personalized Gene Analysis

Our advanced AI-powered personalized gene analysis considers multiple biological and environmental factors to provide targeted genetic recommendations:

Biological Factors

Age-Based Analysis: Different genes become relevant at various life stages, from developmental genes in youth to age-related disease susceptibility genes in later life.

Gender-Specific Genetics: Male and female-specific health risks, including sex-linked genetic conditions and hormone-related genetic variants.

Population Genetics

Ethnicity-Based Recommendations: Population-specific genetic variants including carrier screening relevant to African, Asian, European, Hispanic, Native American, and Middle Eastern ancestries.

Geographic Considerations: Regional genetic adaptations and environmental factors that influence gene expression, including altitude adaptation, UV sensitivity, and disease resistance patterns.

Health Profile Integration

Symptom Analysis: AI processes reported symptoms and health conditions to identify relevant genetic factors for diabetes, cardiovascular disease, cancer predisposition, and neurological conditions.

Family History: Considers familial genetic patterns and hereditary disease risks for comprehensive genetic counseling insights.

Technology Stack

Frontend

Built with Node.js and modern development frameworks, our frontend provides a responsive and intuitive user experience. The interface is designed for both casual users and professional researchers.Our backend provides robust API integration, real-time data processing, and secure data handling.

AI Integration

Advanced AI models provide intelligent analysis, pattern recognition, personalized gene recommendations, and research trend analysis. Our AI considers biological factors including age, gender, ethnicity, and geographic location to deliver personalized genetic insights relevant to specific populations and health profiles.

AI Chat & Natural Language Processing

Our intelligent chat functionality is powered by OpenAI's advanced language models, enabling natural language interactions for genetic research queries. This integration allows users to ask complex questions about genes, receive explanations in plain language, and get AI-assisted interpretations of genetic data. The chat system provides contextual responses based on the comprehensive genetic database, making complex genomic information accessible through conversational interfaces.

Infrastructure

Deployed on Microsoft Azure with Docker containerization, ensuring scalability, reliability, and global accessibility.

Development Team

RN
Rex Njoku
Developer & Founder

Passionate about leveraging technology to advance genetic research and make complex genomic data accessible to researchers worldwide.

Data Sources & Compliance

All genetic data is sourced from publicly available, peer-reviewed databases. We maintain strict compliance with data usage policies and ensure proper attribution to all data sources.

Research Use

This platform is designed for research and educational purposes. All information should be verified through primary sources for clinical or commercial applications (Especially at these early stages of development)

Privacy & Security

We prioritize user privacy and data security. No personal genetic information is stored, and all queries are processed in real-time without data retention.

Future Roadmap

We're continuously improving HumanGeneAI with exciting features planned over time:

  • πŸ”¬ Advanced variant analysis tools
  • πŸ“ˆ Enhanced population genetics data integration
  • πŸ§ͺ Pathway analysis and visualization
  • πŸ“š Literature mining and citation tracking
  • πŸ”— API access for programmatic integration
  • 🌐 Multi-language support
  • πŸ‘₯ Family history analysis integration
  • πŸ₯ Clinical decision support tools

Contact & Support

We value your feedback and are here to help with any questions about HumanGeneAI.

Version: 1.0.0
Last Updated: July 2025